Key result
A genetics-based classification using pairwise evolutionary distances showed striking agreement with expert-based picornavirus taxonomy on species and genus taxa, with a few disagreements.
A genetics-based classification of picornaviruses shows strong agreement with expert taxonomy while proposing new universal thresholds for viral divergence.
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Supports objective viral taxonomy thresholds; leaves open validation across other virus families.
Lauber et al. (2012) studied Picornaviruses (n=1,234). GENETIC classification using pairwise evolutionary distances (PEDs) vs. Expert-based picornavirus taxonomy was evaluated on Agreement between the GENETIC classification and expert-based taxonomy. A genetics-based classification using pairwise evolutionary distances showed striking agreement with expert-based picornavirus taxonomy on species and genus taxa, with a few disagreements.
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