Key result
Male sex linked to ~62% higher odds of hypertension vs female sex, especially with higher BMI.
Why the study?
Little information is known about the effect of BMI on the prevalence of hypertension considering sex differences.
Does male sex interact with body mass index to increase the risk of hypertension differently compared to female sex in Chinese adults?
Cross-Sectional (n=6,330)
Yes
Does male sex interact with body mass index to increase the risk of hypertension differently compared to female sex in Chinese adults?
Male sex is associated with a significantly higher risk of hypertension than female sex, particularly among overweight and obese individuals, suggesting that preventive strategies should target this high-risk group.
Supports targeted screening in overweight Chinese males; leaves open whether sex-BMI interaction is causal or generalizable.
Although many researches regarding risk factors for hypertension have been reported, little information is known about the effect of BMI on the prevalence of hypertension considering sex differences. The aim of this study was to examine the sex difference in the prevalence of hypertension with the predicting indicator BMI. A total number of 6330 subjects in Shaanxi were examined using multivariable logistic regression to study the relationship between genders in different levels of BMI and prevalence of hypertension. Overall, females had a higher prevalence of hypertension than males, being 28.36% and 21.55%, respectively. The mean of blood pressure and the prevalence of hypertension increased as BMI getting larger. The result of multivariable logistic regression showed that obese and overweight males had higher risk of getting hypertension than their female counterparts. Further prevention of hypertension should be focused on obese and overweight males more than females and examining the mechanism of how sex differences influence the prevalence of hypertension.
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Xiao et al. (2019) conducted a cross-sectional in Hypertension (n=6,330). Male sex and high Body Mass Index (overweight/obesity) vs. Female sex was evaluated on Prevalence of hypertension (SBP ≥140 mm Hg or DBP ≥90 mm Hg) (OR 1.618, p=<0.05). Male sex was associated with a 1.618-fold higher odds of having hypertension than female sex on average, particularly in overweight and obese individuals.
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