Key result
Distal coronary microembolization leads to heterogeneous microinfarction, resulting in disproportionate left ventricular dysfunction and perfusion deficits that can be assessed by CMR and MDCT imaging.
Distal coronary microembolization is a significant complication of coronary interventions that causes microinfarction and LV dysfunction, which can be increasingly detected and monitored using advanced non-invasive imaging modalities like CMR and MDCT.
Highlights microembolization risks during PCI; leaves open whether CMR/MDCT monitoring alters management or outcomes.
Annually, an estimated 1,285,000 in-patient angioplasty procedures, 1,471,000 inpatient diagnostic cardiac catheteri-zations and 68,000 inpatient defibrillator implantations are performed. The direct and indirect cost of cardiovascular diseases for 2007 is approximately $431.8 billion. The occurrence of plaque rupture with subsequent microemboli of atherosclerotic and thrombolytic debris into small coronary vessels has been confirmed. Microinfarction results from microemboli that are shed following coronary interventions. The aims of this review are to: 1) detect heterogeneous microinfarction using viability imaging, 2) characterize the consequences of distal coronary microembolization on left ventricle function and perfusion and 3) illustrate the progress of non-invasive imaging modalities in assessing distal coronary microembolization.
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Maythem Saeed (2011) conducted a review in Distal Coronary Microembolization. Distal Coronary Microembolization was evaluated. Distal coronary microembolization leads to heterogeneous microinfarction, resulting in disproportionate left ventricular dysfunction and perfusion deficits that can be assessed by CMR and MDCT imaging.
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