Key result
Percutaneous mitral balloon valvuloplasty significantly reduced interatrial electromechanical delay from 56.4 ± 15.8 ms to 38.3 ± 10.4 ms (p < 0.001) at one week in patients with mitral stenosis.
Why the study?
Does percutaneous mitral balloon valvuloplasty improve interatrial electromechanical delay in patients with moderate to severe mitral stenosis?
Observational (n=65)
No
Does percutaneous mitral balloon valvuloplasty improve interatrial electromechanical delay in patients with moderate to severe mitral stenosis?
Absolute Event Rate: 38.3% vs 56.4%
p-value: p=<0.001
Percutaneous mitral balloon valvuloplasty significantly reduces interatrial electromechanical delay, a surrogate marker for atrial fibrillation risk, in patients with moderate to severe mitral stenosis.
Supports PMBV to mitigate AF risk markers in mitral stenosis; hypothesis-generating without randomized outcome data.
The predisposition to atrial fibrillation (AF) in mitral stenosis (MS) has been demonstrated with several electrocardiographic (increased P-wave dispersion) and echocardiographic parameters (atrial electromechanical delay). After percutaneous mitral balloon valvuloplasty (PMBV), the improvement in echocardiographic parameters related to AF risk is unknown. We aimed to assess the interatrial electromechanical coupling by Tissue Doppler Imaging (TDI) echocardiography in MS before and after PBMV. This study included 45 patients with moderate to severe MS who underwent successful PMBV without complication at our clinic and 20 healthy volunteers as a control group. We compared the two groups in regard to clinical, electrocardiographic and echocardiographic features. The patients with MS were also evaluated one week after PMBV. Interatrial electromechanical delay (EMD) was measured by TDI before and after PMBV and we compared the results. The interatrial EMD (56.4 ± 15.8 vs. 34.6 ± 7.2 ms, p < 0.001) was higher in patients with MS as compared to healthy individuals. The maximum P-wave duration (P-max) and P-wave dispersion (PWD) showed significant positive correlation with the interatrial EMD (r = 0.37, p < 0.05 and r = 0.41, p < 0.05 respectively). There was a highly significant decrease in the interatrial EMD (56.4 ± 15.8 vs. 38.3 ± 10.4 ms, p < 0.001) one week after PBMV. The current study showed significant increase in the interatrial EMD in patients with moderate to severe MS. These changes improved significantly after PMBV.
No takes yet. Share an insight, caveat, or question.
Saad et al. (2015) conducted an observational in Mitral stenosis (n=65). Percutaneous mitral balloon valvuloplasty (PMBV) vs. Baseline (before PMBV) was evaluated on Interatrial electromechanical delay (EMD) (p=<0.001). Percutaneous mitral balloon valvuloplasty significantly reduced interatrial electromechanical delay from 56.4 ± 15.8 ms to 38.3 ± 10.4 ms (p < 0.001) at one week in patients with mitral stenosis.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: