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January 20, 1984Science200 citations

Neuromagnetic Evidence of Spatially Distributed Sources Underlying Epileptiform Spikes in the Human Brain

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DBDaniel S. BarthWSWilliam W. SutherlingJEJerome Engle

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Abstract

Neuromagnetic measurements were performed on 17 subjects with focal seizure disorders. In all of the subjects, the interictal spike in the scalp electroencephalogram was associated with an orderly extracranial magnetic field pattern. In eight of these subjects, multiple current sources underlay the magnetic spike complex. The multiple sources within a given subject displayed a fixed chronological sequence of discharge, demonstrating a high degree of spatial and temporal organization within the interictal focus.

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Cite This Study

Barth et al. (1984) studied this question.

synapsesocial.com/papers/6a208be1a39cd90002cc4126https://doi.org/10.1126/science.6422552
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