Key result
Respondents with a depression diagnosis had significantly poorer Mental Component Summary scores (38.8 vs. 51.8) and greater work productivity impairment compared to those without depression.
Why the study?
Very few large-scale studies have compared health and economic outcomes between individuals with and without depression, and across depression severity groups.
Does a diagnosis of depression and its symptom severity worsen health-related quality-of-life, work productivity, and healthcare utilization in US adults?
Cross-Sectional (n=39,331)
Does a diagnosis of depression and its symptom severity worsen health-related quality-of-life, work productivity, and healthcare utilization in US adults?
Absolute Event Rate: 38.8% vs 51.8%
p-value: p=<0.001
Diagnosed depression in US adults is associated with significantly lower health-related quality of life, greater work productivity loss, and higher healthcare utilization, with the burden increasing alongside symptom severity.
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Depression diagnosis was associated with worse HRQoL and productivity in US adults; confirms burden but leaves causal effects of treatment open.
Jain et al. (2022) conducted a cross-sectional in Depression (n=39,331). Depression diagnosis vs. Without depression diagnosis was evaluated on Mental Component Summary (MCS) score (p=<0.001). Respondents with a depression diagnosis had significantly poorer Mental Component Summary scores (38.8 vs. 51.8) and greater work productivity impairment compared to those without depression.
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