Key result
Closure of a patent foramen ovale with a 25-mm occluder and 6 months of warfarin resulted in no residual atrial shunt or recurrent paradoxical embolization in an 8-year-old girl with AMI.
Case Report (n=1)
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We report an 8-year-old girl who presented with clinical features of an acute myocardial infarction. The angiographic appearance of the coronary arteries was normal. A thrombophilic state caused by a homozygote genotype for the prothrombin G20210A mutation was detected, and a patent foramen ovale (PFO) with right-to-left shunting after Valsalva maneuver was demonstrated by transesophageal contrast echocardiography. No other embolic source was identified. We suggest that paradoxical embolization through a PFO resulted in a myocardial infarction in this young patient with hereditary thrombophilia. We closed the patient's PFO with a 25-mm PFO occluder. She was anticoagulated with warfarin for 6 months. After 6 months, a contrast echocardiogram showed no evidence of residual atrial shunt. There has been no evident recurrent paradoxical embolization.
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Carano et al. (2004) conducted a case report in Acute myocardial infarction (n=1). PFO closure and warfarin was evaluated on Residual atrial shunt and recurrent paradoxical embolization. Closure of a patent foramen ovale with a 25-mm occluder and 6 months of warfarin resulted in no residual atrial shunt or recurrent paradoxical embolization in an 8-year-old girl with AMI.
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