Population
128 human enterovirus 71 strains isolated from 1970 to 2002, including recent isolates from the Asia-Pacific…
Design
Other
Key result
Phylogenetic analysis of HEV71 strains revealed that multiple genogroups, including B3, B4, C1, C2, and a newly identified C3, have co-circulated and caused major outbreaks in the Asia-Pacific region since 1997.
Authors
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Supports continued HEV71 surveillance in Asia-Pacific; leaves open genogroup-specific prevention strategies.
Observational (n=128)
This molecular epidemiology study demonstrates that multiple genogroups of HEV71 have co-circulated in the Asia-Pacific region, highlighting the need for continued virological surveillance.
Cardosa et al. (2003) conducted an observational in Human enterovirus 71 (HEV71) infection (n=128). HEV71 strain isolation and sequencing was evaluated on Genogroup classification based on VP1 and VP4 gene sequences. Phylogenetic analysis of HEV71 strains revealed that multiple genogroups, including B3, B4, C1, C2, and a newly identified C3, have co-circulated and caused major outbreaks in the Asia-Pacific region since 1997.
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