Population
Seven female Sprague-Dawley rats (280+/-6 g)
Comparison
Hypovolemic hypotension induced by arterial… vs Normotensive conditions
Design
Preclinical
Authors
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Hypotension may impair muscle microvascular oxygenation at contraction onset in animals; leaves open translation to human exercise physiology.
Hypovolemic hypotension constrains the increase of skeletal muscle oxygen delivery relative to utilization at the onset of contractions, leading to decreased microvascular oxygen pressure.
Behnke et al. (2005) studied this question.
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