Key result
Preoperative pulse pressure ≥80 mm Hg was not associated with an increased risk of major adverse cardiovascular events after lower extremity bypass surgery (OR 1.36; 95% CI 0.62-2.90; P=0.44).
Why the study?
Does increased preoperative pulse pressure predict postoperative MACEs in patients undergoing lower extremity vascular bypass surgery?
Population
412 consecutive patients with peripheral vascular disease undergoing lower extremity vascular bypass surgery
Comparison
Preoperative pulse pressure (PP) ≥80 mm Hg vs Preoperative pulse pressure (PP) <80 mm Hg
Design
Cohort
Follow-up
perioperative/in-hospital
Authors
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Preoperative pulse pressure should not guide MACE risk stratification before lower extremity bypass; leaves open validation in larger prospective cohorts.
Cohort (n=412)
No
Does increased preoperative pulse pressure predict postoperative MACEs in patients undergoing lower extremity vascular bypass surgery?
Odds Ratio: 1.36 (95% CI 0.62–2.9)
Absolute Event Rate: 8.8% vs 5.7%
p-value: p=0.44
Preoperative pulse pressure is not a significant predictor of major perioperative adverse cardiovascular outcomes in patients undergoing lower extremity vascular bypass surgery.
Asopa et al. (2011) conducted a cohort in Peripheral vascular disease undergoing lower extremity vascular bypass surgery (n=412). Preoperative pulse pressure ≥80 mm Hg vs. Preoperative pulse pressure <80 mm Hg was evaluated on Postoperative major adverse cardiovascular events (myocardial infarction, congestive heart failure, stroke, and in-hospital mortality) (OR 1.36, 95% CI 0.62-2.90, p=0.44). Preoperative pulse pressure ≥80 mm Hg was not associated with an increased risk of major adverse cardiovascular events after lower extremity bypass surgery (OR 1.36; 95% CI 0.62-2.90; P=0.44).
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