Key result
This review analyzes the effectiveness and economic implications of irbesartan for preventing or delaying organ damage in hypertensive patients.
Why the study?
Does irbesartan prevent or delay organ damage and provide cost-effectiveness in hypertensive patients compared to other available antihypertensive drugs?
Does irbesartan prevent or delay organ damage and provide cost-effectiveness in hypertensive patients compared to other available antihypertensive drugs?
This review evaluates the clinical efficacy and economic implications of irbesartan for preventing organ damage in hypertensive patients, particularly those with metabolic complexities.
May inform irbesartan selection in hypertension with organ-risk; leaves open updated cost-effectiveness trials versus contemporary agents.
High blood pressure is a very common problem in the adult and elderly population, both in developed and developing countries. A relatively large number of drug classes are available to treat this condition and prevent its complications, which are not only more frequent in the aforementioned patients but also those affected by metabolic syndrome and/or Type 2 diabetes. Irbesartan is an angiotensin-receptor blocker class drug with good antihypertensive efficacy and specific pharmacological characteristics, whose efficacy has been more deeply evaluated in metabolically complex hypertensive patients. In this review, the authors will analyze its effectiveness in preventing or delaying organ damage in hypertensive patients, with a closer look at the economic implications of treating hypertension with irbesartan in the context of available antihypertensive drugs.
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Borghi et al. (2015) conducted a review in Hypertension. Irbesartan vs. available antihypertensive drugs was evaluated on Organ damage and economic implications. This review analyzes the effectiveness and economic implications of irbesartan for preventing or delaying organ damage in hypertensive patients.
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