Key result
Novel antiarrhythmic therapies based on rational drug design, gene therapy, and molecular biology are emerging as promising approaches for treating cardiac arrhythmias.
Design
Review
Authors
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Requires randomized validation before clinical use; leaves open mechanism-specific arrhythmia therapies pending efficacy data.
Advances in understanding the cellular and molecular biology of cardiac arrhythmias are paving the way for novel mechanism-specific pharmacological and gene therapies.
Members of the Sicilian Gambit (2001) conducted a review in Cardiac arrhythmias. Novel antiarrhythmic therapies was evaluated. Novel antiarrhythmic therapies based on rational drug design, gene therapy, and molecular biology are emerging as promising approaches for treating cardiac arrhythmias.
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