Key result
Increasing aortic valve calcification scores in elderly males were significantly associated with decreased aortic valve area (P=0.0001), increased mean gradient (P=0.0001), and AVR (P<0.0001).
Why the study?
Aortic valve calcification detected by non-contrast computed tomography associates with morbidity and mortality in aortic valve stenosis, but its importance in the general population is sparsely evaluated.
Does increasing aortic valve calcification score on non-contrast CT associate with adverse echocardiographic findings and aortic valve replacement in elderly males?
Cross-Sectional (n=828)
Does increasing aortic valve calcification score on non-contrast CT associate with adverse echocardiographic findings and aortic valve replacement in elderly males?
p-value: p=0.0001
In elderly males from the general population, increasing aortic valve calcification scores on non-contrast CT strongly correlate with echocardiographic signs of aortic stenosis and the need for aortic valve replacement.
May support AVC for AS risk assessment in elderly males; leaves open prospective validation before clinical adoption.
No takes yet. Share an insight, caveat, or question.
Khurrami et al. (2021) conducted a cross-sectional in Aortic valve calcification (n=828). Aortic valve calcification (AVC) score vs. Lower AVC score categories was evaluated on Echocardiographic findings (LA dilatation, LV hypertrophy, AVA, peak velocity, mean gradient) and AVR (p=0.0001). Increasing aortic valve calcification scores in elderly males were significantly associated with decreased aortic valve area (P=0.0001), increased mean gradient (P=0.0001), and AVR (P<0.0001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: