Why the study?
Is there a higher seroprevalence of B. burgdorferi antibodies in patients with pulmonary sarcoidosis compared to healthy blood donors?
Population
60 patients suffering from sarcoidosis
Comparison
Serological examination for anti-Borrelia… vs 1,000 regular blood donors of the city of Hamburg
Design
Case-control
Authors
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Does not support Borrelia as sarcoidosis etiology; challenges infectious hypothesis and leaves other triggers open for study.
Is there a higher seroprevalence of B. burgdorferi antibodies in patients with pulmonary sarcoidosis compared to healthy blood donors?
The study found no evidence to support a causal relationship between Borrelia burgdorferi infection and pulmonary sarcoidosis.
Martens et al. (1997) studied this question.
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