Key result
Primary peritonitis linked to ~78% higher postoperative mortality versus secondary peritonitis.
Why the study?
The significance of the speed of development of purulent peritonitis had not yet been studied.
Does the rate of development of purulent peritonitis impact treatment outcomes in patients with acute surgical pathology?
Observational (n=113)
Does the rate of development of purulent peritonitis impact treatment outcomes in patients with acute surgical pathology?
Absolute Event Rate: 62.5% vs 35.1%
p-value: p=<0.05
The rate of development of purulent peritonitis significantly impacts patient outcomes, with rapid development (primary peritonitis) associated with higher mortality and complication rates.
Rapid peritonitis onset was associated with higher mortality; hypothesis-generating for timing-based risk stratification, pending prospective validation.
In recent years, the periodic literature suggests dividing peritonitis based on the speed of its development into primary peritonitis (PP) and secondary peritonitis (SP). The significance of the speed of development of purulent peritonitis has not been studied yet. The aim of the study was to assess the impact of the rates of peritonitis development on treatment outcomes in patients with purulent peritonitis. Materials and Methods: A total of 113 patients with purulent peritonitis were analyzed. The incidence of peritonitis with varying rates of development, its etiological structure, and treatment outcomes were studied. Results: The PP group included 56 (49.6%) patients, while the SP group included 57 (50.4%) patients. In the PP group, 64.3% of cases had pathology of the upper gastrointestinal tract as the source of peritonitis. In 35.7% of cases, the source of abdominal cavity contamination was the lower gastrointestinal tract and structures localized outside the digestive tract. In the SP group, 70.1% of patients had the lower gastrointestinal tract as the source of peritonitis. In 29.9% of cases, the source was identified as the upper gastrointestinal tract and structures localized outside the digestive tract. The postoperative mortality rate in the PP group reached 62.5%, which correlated with a frequency of somatic complications of 69.4%. Mortality in the SP group was 35.1% (p < 0.05), with somatic complications recorded in 40.3% of cases (p < 0.05). Conclusion: The rates of development of purulent peritonitis have a significant impact on treatment outcomes for patients.
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Bokarev et al. (2025) conducted an observational in Purulent peritonitis (n=113). Primary peritonitis (rapid development) vs. Secondary peritonitis was evaluated on Postoperative mortality rate (p=<0.05). Primary peritonitis (rapid development) was associated with a significantly higher postoperative mortality rate compared to secondary peritonitis (62.5% vs 35.1%, p<0.05).
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