Retrospective case-control study finds key predictive risk factors for cerebral palsy in preschool children, suggesting implications for early intervention.
The purpose of this study was to assess a model of risk for cerebral palsy (CP) in preschool children. The research was structured as a retrospective case-control study in which cases (n = 112) were children with CP while controls (n = 153) were either friend referrals or population-based. Data were collected via structured telephone interviews. While significant associations with CP were found on univariate analyses for a number of variables, only four variables--birth weight/gestational age, 5-min APGAR, medication for miscarriage, and urinary tract infection during pregnancy--were found predictive in multivariate analysis. These variables accounted for 36% of the log-likelihood explained by the model.
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Polivka et al. (1993) studied this question.
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