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BACKGROUND: Given the exponential increase in clinical data, which accounts for around 30% of global data volume, effective information management has become crucial to ensuring robust interoperability. This trend is further expedited by implementing consumer-oriented Internet of Things platforms, contributing to the growth of the 8. 3 trillion healthcare industry. These advancements, combined with challenges such as heterogeneous data formats and a lack of incentives, necessitate the development of pragmatic infrastructures and tools that harness contemporary clinical standards like Fast Healthcare Interoperability Resources (FHIR). OBJECTIVE: This study aims to present a modular conversion pipeline employing a templating strategy for translating clinical data into the FHIR model. Emphasis is placed on utilizing a standard mapping specification like FHIR Mapping Language. This ensures essential properties such as platform independence, portability, and code reusability. METHODS: The pipeline was developed incrementally, dividing its core functionalities into five modules: Input, Refinement, Mapping, Validation, and Export. These were subsequently validated by converting a dataset from a prosthetic fitting and rehabilitation center to demonstrate the approach's validity in a real-world data context. RESULTS: A total of 1962 hospital stay records of 1006 unique patients were converted successfully to 15 distinct types of FHIR resources. The successful conversion states the pipeline's effectiveness, additionally showcasing its capabilities for enhancing semantic interoperability and facilitating the reuse of real-world data. CONCLUSION: Our approach emerges as a modular data conversion framework that addresses the limitations of existing solutions, making significant contributions to the creation of standardized, interoperable, and high-quality clinical datasets that serve as a foundation for further work.
Marfoglia et al. (Mon,) studied this question.