The 2012 updated Universal Definition of Myocardial Infarction introduces a critical distinction between myocardial ischemia and injury, particularly relevant with the use of high-sensitivity troponin assays.
Refines MI diagnosis amid high-sensitivity troponin assays; extends prior universal definitions for PCI- and CABG-related events.
At the 2012 European Society of Cardiology (ESC) Conference in Munich, the updated Universal Definition of myocardial infarction was presented for the first time and was then published simultaneously in five medical journals (European Heart Journal, Circulation, Journal of American College of Cardiology, Nature Reviews Cardiology, Global Heart). Major changes in this updated version include the differentiation between myocardial ischemia and myocardial injury, which gives credit to the relatively large number of patients with troponin positive test results, especially when measured with high sensitivity assays, in patients without myocardial ischemia. Another important topic is the revised criteria for the diagnoses of acute myocardial ischemia related to percutaneous coronary intervention (PCI) and coronary arterial bypass grafting (CABG).
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Thygesen et al. (2013) conducted a review in Acute Myocardial Infarction. Universal Definition of Acute Myocardial Infarction was evaluated. The updated Universal Definition of myocardial infarction differentiates myocardial ischemia from injury and revises diagnostic criteria for PCI- and CABG-related acute myocardial ischemia.
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