Key result
MI survivors aged 50-64 with additional atherothrombotic risk factors had a higher cumulative incidence of MI, stroke, or death compared to those without (20.8% vs 12.2%) over a mean 2-year follow-up.
Population
13,492 subjects with a history of myocardial infarction, aged 50-64 years, who were MI- and stroke-free for…
Design
Cohort
Follow-up
up to 5 years (mean: 2.0 years)
Authors
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High-risk MI survivors with extra factors face ongoing events; hypothesis-generating for targeted long-term prevention trials.
Cohort (n=13,492)
Absolute Event Rate: 20.8% vs 12.2%
High-risk MI survivors who are event-free for ≥1 year remain at substantial risk for cardiovascular events and incur high healthcare costs, emphasizing the need for long-term secondary prevention.
Kern et al. (2015) conducted a cohort in Post-myocardial infarction (n=13,492). Atherothrombotic risk factors (type 2 diabetes, additional prior MI, non-end-stage renal disease) vs. Without selected atherothrombotic risk factors was evaluated on Composite of MI, stroke, and all-cause death. MI survivors aged 50-64 with additional atherothrombotic risk factors had a higher cumulative incidence of MI, stroke, or death compared to those without (20.8% vs 12.2%) over a mean 2-year follow-up.
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