Key result
African American ethnicity and male sex were associated with early onset and rapid elevation of blood pressure and cardiac mass compared to European American ethnicity and female sex.
Why the study?
To introduce a multiracial longitudinal cohort initiated in childhood to identify precursors and pathophysiologic mechanisms contributing to preclinical CVD manifestations.
Population
300 African Americans and 307 European Americans recruited as youth in the Metro Augusta area
Design
Multiracial longitudinal cohort study
Follow-up
thirty-year span
Authors
Loading...
May warrant earlier BP monitoring in African American males; leaves open causal mechanisms and intervention effects.
Cohort (n=607)
The Augusta Heart Study provides a comprehensive 30-year longitudinal database of a multiracial youth cohort, demonstrating early racial and sex differences in the development of cardiovascular risk factors like left ventricular mass.
George et al. (2019) conducted a cohort in Cardiovascular disease precursors (n=607). African American ethnicity and male sex vs. European American ethnicity and female sex was evaluated on Left ventricular mass and blood pressure. African American ethnicity and male sex were associated with early onset and rapid elevation of blood pressure and cardiac mass compared to European American ethnicity and female sex.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: