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September 2, 1983

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Haloperidol-Induced Plasticity of Axon Terminals in Rat Substantia Nigra

FBFrancine M. BenešHarvard University PPPeter A. PaskevichHarvard University VDValerie B. DomesickBoston University

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Resumen

An electron micrographic morphometric analysis of nerve endings in substantia nigra of rats repeatedly treated with haloperidol was performed. Although most parameters showed no difference, drug-treated animals exhibited a significant shift in the distribution of relative numbers of axon terminals, suggesting neuroleptic-induced axon-collateral sprouting.

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Haloperidol-Induced Plasticity of Axon Terminals in Rat Substantia Nigra | Synapse

Cite This Study

Beneš et al. (Fri,) studied this question.

synapsesocial.com/papers/6a20976c48884d7e5691137a https://doi.org/https://doi.org/10.1126/science.6879197

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