Intracoronary Blood Flow Velocity and Transstenotic Pressure Drop in an Awake Human Being During Coronary Vasodilation
Why the study?
Can fluid dynamic equations based on quantitative arteriography accurately describe the hemodynamics of a coronary stenosis in humans?
Population
1 awake human being with a coronary stenosis
Comparison
Coronary vasodilation during measurement of… vs Rest (baseline measurement)
Design
Case_report
Authors
Discussion
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Member takes
Implication
Offers preliminary support for model-based stenosis evaluation; leaves open need for prospective validation before broader use.
Structured PICO
Can fluid dynamic equations based on quantitative arteriography accurately describe the hemodynamics of a coronary stenosis in humans?
P
Population
1 awake human being with a coronary stenosis
I
Intervention
Coronary vasodilation during measurement of intracoronary Doppler blood flow velocity and transstenotic pressure drop
C
Comparator
Rest (baseline measurement)
O
Outcome
Hemodynamics of a coronary stenosis (pressure drop and blood flow velocity)surrogate
This report provides the first in-human confirmation that fluid dynamic equations accurately describe coronary stenosis hemodynamics.
Cite This Study
Zijlstra et al. (1988) studied this question.