Key result
Percutaneous edge-to-edge repair evolves from open surgery to treat high-risk functional MR.
Why the study?
A critical review of surgical and early percutaneous repair data was needed to elucidate the clinical role and future development potential of edge-to-edge repair for mitral regurgitation.
The edge-to-edge technique has evolved from open surgical repair to percutaneous approaches like MitraClip, offering a minimally invasive option for high-risk patients with functional mitral regurgitation.
Answers are grounded in this paper and cite their sources.
Supports percutaneous edge-to-edge repair for high-risk functional MR; extends surgical data while leaving comparative durability open.
The edge-to-edge technique is a versatile procedure for mitral valve repair. Its technical simplicity has been the prerequisite for the development of a number of transcatheter technologies to perform percutaneous mitral valve repair. The evolution from a standard open heart surgical to percutaneous procedure involved the application of the technique in minimally invasive robotic surgery and direct access (transatrial) off-pump suture-based repair and finally in the fully percutaneous approach with either suture-based or device (clip)-based approach. The MitraClip (Abbott Vascular, Menlo Park, California) is currently available for clinical use in Europe, and it is mainly applied to treat high-risk patients with functional mitral regurgitation. A critical review of the surgical as well as the early percutaneous repair data is necessary to elucidate the clinical role and the potential for future developments of the edge-to-edge repair in the treatment of mitral regurgitation.
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Maisano et al. (2011) conducted a review in Mitral regurgitation. Percutaneous mitral valve interventions (edge-to-edge repair) vs. Open heart surgical repair was evaluated. The edge-to-edge technique has evolved from open heart surgery to fully percutaneous approaches like the MitraClip, which is used to treat high-risk patients with functional mitral regurgitation.
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