Population
Caenorhabditis elegans (nematode) mutants (unc-13, unc-54 I, unc-15 I)
Comparison
sup-7(st5) allele (suppressor mutation) vs sup-5(e1464) allele or wild-type
Design
Preclinical
Authors
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Supports sup-7 as informational suppressor akin to sup-5; leaves open mechanisms and relevance beyond C. elegans.
Identification of sup-7 X as a second informational suppressor gene in C. elegans that acts on null alleles similarly to sup-5.
R Waterston (1981) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: