What question did this study set out to answer?

This research aims to characterize the receptors for vascular endothelial growth factor in endothelial cells.

Characterization of the receptors for vascular endothelial growth factor.

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Randomized trial characterizes vEGF receptors in endothelial cells, indicating their binding properties.

This research aims to characterize the receptors for vascular endothelial growth factor in endothelial cells.
Binding and cross-linking techniques were used to analyze vEGF receptors on bovine endothelial cells.
Scatchard analysis revealed two high-affinity binding sites with specific dissociation constants.
The effect of glycosylation on receptor expression was tested using tunicamycin.
Two types of high-affinity binding sites were identified, with dissociation constants of 10(-12) M and 10(-11) M.
A high molecular weight complex of 225 kDa was formed, with additional complexes at 170 and 195 kDa.
Glycosylation is essential for functional receptor expression, as shown by inhibition when cells were treated with tunicamycin.

Vaisman et al. (1990) studied this question.

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