Key result
This review summarizes the clinical, epidemiological, and pathogenetic relationships between atrial fibrillation and diabetes mellitus, highlighting mechanisms such as fibrosis and oxidative stress.
This review summarizes the clinical features, gender differences, and pathogenetic mechanisms linking atrial fibrillation and diabetes mellitus.
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Links AF-DM via fibrosis; leaves open whether targeting these pathways improves outcomes.
The article summarizes the main clinical and theoretical data on features of atrial fibrillation (AF) course in combination with diabetes mellitus (DM). The potential relationship between these comorbid conditions is analyzed on the basis of the results of epidemiological and randomized studies, the gender features of the course of AF in this category of patients are assessed. Particular attention is paid to pathogenetic bases of AF development in DM (fibrosis, neurohumoral regulation, impaired energy metabolism of cardiomyocytes, oxidative stress, genetic factors, electrolyte metabolism disorders).
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Serik et al. (2021) conducted a review in Atrial fibrillation and diabetes mellitus. Diabetes mellitus was evaluated. This review summarizes the clinical, epidemiological, and pathogenetic relationships between atrial fibrillation and diabetes mellitus, highlighting mechanisms such as fibrosis and oxidative stress.
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