Antitumor factors of natural origin and some approaches to the develop-ment of effective regimens of phytotherapy in oncology

The review examines information about factors of natural origin that are promising for the purposes of clinical oncology, and as well as some modern approaches to the development of effective methods of phytotherapy for the treatment of cancer patients. The data on a number of the most famous and widespread phytochemicals in nature, which are currently undergoing the first phases of clinical trials, are presented. The article analyzes information about domestic studies to identify promising antitumor factors and means of accompanying treatment, known and original approaches to the development of effective regimens of phytotherapy. Some results of studies carried out with the participation of the authors in a number of research institutions in Russia - the All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (FGBNU VILAR, Moscow), National Medical Research Center of Oncology named after N.N. Blokhin (N.N. Blokhin National Medical Research Center of Oncology, Moscow), National Medical Research Center of Oncology in Rostov-on-Don, Southern Scientific Center of the Russian Academy of Sciences (SSC RAS, Rostov-on-Don ), Southern Federal University (SFedU, Rostov-on-Don). The review provides information on the literature indexed in the Scopus, WoS, Pubmed, RSCI databases. More than 60% of works were published in the last 5 years, 40% of works were published in the last 3 years.