Key result
The distribution of local conduction velocities during coronary sinus pacing showed large similarity between patients (median CVs 0.26-0.36 mm/ms), limiting its ability to identify atrial fibrillation substrate complexity.
Observational (n=7)
Calculating local conduction velocity during coronary sinus pacing is feasible, but the resulting CV distributions showed large similarities between patients, limiting its immediate utility as a standalone marker for AF substrate complexity.
Limits CS pacing CV as standalone AF substrate marker; leaves open refined mapping in prospective studies.
Methods: LA activation times were recorded for 7 AF patients during coronary sinus (CS) pacing before PVI using a Pentaray catheter. Activation times were relative to the CS pacing spike. LA activation locations were triangularized to calculate CV: the local direction and speed of the activation wave front. CV was quantified by the total CV distribution.
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Rosmalen et al. (2019) conducted an observational in Atrial fibrillation (n=7). Local conduction velocity mapping during coronary sinus pacing was evaluated on Total conduction velocity (CV) distribution. The distribution of local conduction velocities during coronary sinus pacing showed large similarity between patients (median CVs 0.26-0.36 mm/ms), limiting its ability to identify atrial fibrillation substrate complexity.
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