Key result
Obesity and altered adipose tissue metabolism, including changes in adipokine levels, are associated with increased cardiovascular morbidity and mortality in patients with chronic kidney disease.
Population
Patients with chronic kidney disease (CKD) and patients on dialysis
Design
Review
Authors
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May identify adiposity as a modifiable CV target in CKD; leaves open whether adipokine interventions improve outcomes.
Adipose tissue and its derived adipokines play a significant role in the cardiovascular morbidity and mortality of patients with chronic kidney disease.
Iglesias et al. (2010) conducted a review in Chronic kidney disease. Obesity and adipose tissue accumulation was evaluated. Obesity and altered adipose tissue metabolism, including changes in adipokine levels, are associated with increased cardiovascular morbidity and mortality in patients with chronic kidney disease.
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