Key result
Arrhythmogenic right ventricular dysplasia/cardiomyopathy is a heritable condition where approximately 50-60% of patients have an identifiable pathogenic mutation in desmosome-related genes.
This review summarizes the current understanding of ARVD/C, emphasizing the role of genetic mutations, the 2010 revised diagnostic criteria, and the importance of restricting strenuous physical activity in management.
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Supports genetic counseling in ARVD/C families; leaves open full genetic architecture and penetrance modifiers.
Brittney Murray (2012) conducted a review in Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C). Arrhythmogenic right ventricular dysplasia/cardiomyopathy is a heritable condition where approximately 50-60% of patients have an identifiable pathogenic mutation in desmosome-related genes.
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