Answers are grounded in this paper and cite their sources.
Acute isoniazid overdose and toxicity may be complicated by convulsions and death. Six patients are reported, one of whom ingested simultaneously 15 gm of isoniazid and 5 gm of pyridoxine hydrochloride (vitamin B6); no convulsions resulted. In the light of this and other experience, suggestions are made for the use of pyridoxine in the treatment and prevention of acute isoniazid poisoning.
No takes yet. Share an insight, caveat, or question.
COYER et al. (1976) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: