Key result
The MSCT-based OSACA ratio demonstrated significantly higher discriminatory performance for paravalvular leakage ≤ trace compared to the TEE-based ratio (AUC 0.87 vs 0.69; p=0.028).
Why the study?
Does MSCT-based aortic annular measurement (OSACA ratio) improve the prediction and prevention of paravalvular leakage compared to TEE in patients undergoing TAVR?
Population
45 consecutive patients undergoing transcatheter aortic valve replacement, divided into an initial cohort…
Comparison
Electrocardiogram-gated multi-slice computed… vs Transesophageal echocardiography-based aortic…
Design
Cohort
Authors
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MSCT-based OSACA ratio may aid paravalvular leakage prediction after TAVR; leaves open whether it should replace TEE-based sizing.
Observational (n=45)
Does MSCT-based aortic annular measurement (OSACA ratio) improve the prediction and prevention of paravalvular leakage compared to TEE in patients undergoing TAVR?
Absolute Event Rate: 0.87% vs 0.69%
p-value: p=0.028
MSCT-based sizing using the OSACA ratio provides superior discrimination for predicting and preventing paravalvular leakage after TAVR compared to TEE-based sizing.
Maeda et al. (2013) conducted an observational in Paravalvular leakage following transcatheter aortic valve replacement (n=45). MSCT-based OSACA ratio vs. TEE-based OSACA ratio was evaluated on Discriminatory performance (AUC) for paravalvular leakage ≤ trace (p=0.028). The MSCT-based OSACA ratio demonstrated significantly higher discriminatory performance for paravalvular leakage ≤ trace compared to the TEE-based ratio (AUC 0.87 vs 0.69; p=0.028).
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