Key result
Off-pump implantation of a self-expandable valved stent in the mitral position was technically feasible in 8 adult pigs, with correct positioning confirmed in 7 out of 8 animals.
Why the study?
Does off-pump mitral valve replacement using double-crowned valved stents demonstrate feasibility in an adult pig model?
Population
Adult pigs (n=8)
Design
Preclinical
Follow-up
up to 3 hours (mean survival time 97.5+/-56.3 min)
Authors
Loading...
Supports preclinical mitral stent development; leaves open human translation of off-pump replacement.
Does off-pump mitral valve replacement using double-crowned valved stents demonstrate feasibility in an adult pig model?
Off-pump implantation of a self-expandable double-crowned valved stent in the mitral position is technically feasible in a porcine model, providing early preclinical evidence for transcatheter mitral valve replacement.
Ma et al. (2005) studied Mitral valve replacement (n=8). Double-crowned valved stents was evaluated on Feasibility of off-pump mitral valve replacement. Off-pump implantation of a self-expandable valved stent in the mitral position was technically feasible in 8 adult pigs, with correct positioning confirmed in 7 out of 8 animals.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: