Extending Mechanistic Routes in Heterazolium Catalysis–Promising Concepts for Versatile Synthetic Methods

A broad spectrum of valuable cyclic and acyclic products are available in diastereo- and/or enantioselective form by sustainable, organocatalytic processes like the heterazolium-catalyzed transformations shown in the scheme. The carbene-mediated generation of activated carboxylate intermediates provides new possibilities for the straightforward synthesis of multifunctionalized compounds.