Key result
ADP release in phasic and tonic smooth muscles is a regulated step with strain- and dephosphorylation-dependence, contributing to the high economy of force characteristic of smooth muscle.
Population
Smooth muscle cross-bridges (phasic and tonic smooth muscles)
Design
Review
Authors
Loading...
May inform vascular smooth muscle models; leaves open clinical relevance for tone disorders.
This review highlights that ADP release in smooth muscle is regulated by strain and dephosphorylation, explaining the high economy of force characteristic of smooth muscle contraction.
Holmes et al. (2004) conducted a review in Smooth muscle contraction. Smooth muscle myosin regulation was evaluated. ADP release in phasic and tonic smooth muscles is a regulated step with strain- and dephosphorylation-dependence, contributing to the high economy of force characteristic of smooth muscle.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: