Population
Skinned mammalian skeletal muscle fibres (rabbit psoas muscle)
Comparison
Decreased pH at high temperature vs Decreased pH at low temperature
Design
Preclinical
Authors
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Challenges acidosis role in physiological muscle fatigue; hypothesis-generating for human performance models.
The inhibitory effect of acidosis on muscle function is markedly reduced at near-physiological temperatures, suggesting pH plays a less important role in muscle fatigue than previously thought.
Pate et al. (1995) studied this question.
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