What does this research mean for the field?

Electrostatic interactions govern the liquid-liquid phase separation of HP1α, where specific binding partners modulate droplet charge and hinge-NTE interactions to drive a structural change from a compacted to an extended dimer conformation. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

June 20, 2022Open Access

Molecular interactions underlying the phase separation of HP1α: Role of phosphorylation, ligand and nucleic acid binding

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Authors

CHCheenou HerUniversity of California, San Diego TPTien M. PhanTexas A&M University NJNina JovicLehigh University

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Cite This Study

Her et al. (2022) studied this question.

synapsesocial.com/papers/6a20ad5f515be2b4c6f9e3cf https://doi.org/10.1101/2022.06.20.496886

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June 20, 2022Open Access

Molecular interactions underlying the phase separation of HP1α: Role of phosphorylation, ligand and nucleic acid binding

View Full Paper

Ask AI

Bookmark

Authors

CHCheenou HerUniversity of California, San Diego TPTien M. PhanTexas A&M University NJNina JovicLehigh University

Discussion

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Her et al. (2022) studied this question.

synapsesocial.com/papers/6a20ad5f515be2b4c6f9e3cf https://doi.org/10.1101/2022.06.20.496886

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