Why the study?
Did inpatient mortality from acute myocardial infarction change between 1982 and 1992 with the increasing uptake of evidence-based treatments?
Population
Patients admitted with a confirmed acute myocardial infarction during 1982-1984 and 1989-1992 to two…
Comparison
Temporal trends in management vs Historical comparison (1982-1984 vs. 1989-1992)
Design
Cohort
Follow-up
Inpatient stay
Authors
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Inpatient AMI mortality remained stable despite rising evidence-based therapy use; leaves open real-world implementation gaps or population differences versus trials.
Did inpatient mortality from acute myocardial infarction change between 1982 and 1992 with the increasing uptake of evidence-based treatments?
Despite the increased adoption of evidence-based therapies such as aspirin, beta-blockers, and thrombolysis between 1982 and 1992, inpatient mortality for acute myocardial infarction did not significantly change in this unselected population.
Brown et al. (1997) studied this question.