Key result
Patients with suspected myocarditis had higher serum anti-cardiac troponin I autoantibody titers compared to healthy volunteers, with even higher levels observed in HCV-infected patients.
Observational (n=2,430)
Yes
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Elevated autoantibody titers against cardiac troponin I are detected in patients with myocarditis, particularly those with concurrent hepatitis C infection, suggesting a link to active myocardial inflammation.
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Matsumori et al. (2011) conducted an observational in Myocarditis and Heart Failure (n=2,430). Heart failure and suspected myocarditis vs. Healthy volunteers was evaluated on Serum Anti-cTnIAAB titer (AU) (p=<0.01). Patients with suspected myocarditis had higher serum anti-cardiac troponin I autoantibody titers compared to healthy volunteers, with even higher levels observed in HCV-infected patients.
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