Key result
Infection with the EV-G CH/17GXQZ/2017 strain in 7-day-old piglets caused clinical neurological symptoms, mild hyperemia and Nissl bodies vacuolization in the cerebrum, and significantly decelerated weight gain.
Why the study?
The genetic and pathogenic characteristics of Enterovirus G itself are not fully understood.
Population
Seven-day-old piglets
Comparison
Oral inoculation with the CH/17GXQZ/2017 strain
Design
Preclinical animal inoculation and in vitro study
Authors
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Supports neurovirulence of EV-G CH/17GXQZ/2017 in neonatal piglets; hypothesis-generating for swine disease surveillance and control.
The EV-G strain CH/17GXQZ/2017 isolated from China is pathogenic to neonatal piglets, causing neurological symptoms and reduced weight gain.
Mi et al. (2021) studied Porcine Enterovirus G infection (n=8). EV-G CH/17GXQZ/2017 strain vs. Mock (cell culture media) was evaluated on Pathogenicity (clinical symptoms and weight gain). Infection with the EV-G CH/17GXQZ/2017 strain in 7-day-old piglets caused clinical neurological symptoms, mild hyperemia and Nissl bodies vacuolization in the cerebrum, and significantly decelerated weight gain.
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