Key result
Maintained wakefulness under constant routine confirmed the presence of an endogenous circadian rhythm of heart rate but a consistent absence of an endogenous circadian variation of blood pressure.
Why the study?
Does maintained wakefulness under constant routine reveal an endogenous circadian rhythm of blood pressure and heart rate in healthy young subjects?
Population
6 normotensive, healthy young subjects
Design
Other
Follow-up
24 hours (repeated 5 times)
Authors
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Suggests behavioral factors drive 24-h BP unlike HR; leaves open endogenous BP role in disease states.
Observational (n=6)
Does maintained wakefulness under constant routine reveal an endogenous circadian rhythm of blood pressure and heart rate in healthy young subjects?
The 24-hour profile of blood pressure is driven by environmental and behavioral factors such as sleep, lacking an endogenous circadian component, unlike heart rate.
Dongen et al. (2001) conducted an observational in Healthy (n=6). Maintained wakefulness (constant routine) was evaluated on Endogenous circadian variation of blood pressure and heart rate. Maintained wakefulness under constant routine confirmed the presence of an endogenous circadian rhythm of heart rate but a consistent absence of an endogenous circadian variation of blood pressure.
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