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June 30, 2022Tuberculosis Research and TreatmentOpen Access

Yield and Coverage of Active Case Finding Interventions for Tuberculosis Control:A Systematic Review and Meta-analysis

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Authors

RDRuth DeyaUniversity of WashingtonLMLinnet N. MaseseUniversity of NairobiWJWalter JaokoUniversity of Nairobi

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Implication

Systematic review identifies diagnostic approaches that enhance tuberculosis screening yield and coverage in various settings.

Key Points

  • To identify optimal populations, settings, and diagnostic approaches in active case finding for tuberculosis control.
  • Systematic review of 3,972 publications, narrowing to 224 that met predefined criteria.
  • Calculated pooled coverage of 93.5% and pooled yield of active TB at 3.2%.
  • Compared diagnostic methodologies for yield assessment, including symptom screening and laboratory testing.
  • Pooled coverage was 93.5% among targeted individuals.
  • Highest yield was recorded in internally-displaced persons camps (15.6%) and healthcare facilities (6.9%).
  • Screening individuals using laboratory tests (microscopy, culture, Xpert) yielded 3.7% more cases than symptom screening.

Cite This Study

Deya et al. (2022) studied this question.

synapsesocial.com/papers/6a20b23b920e38fa09f9ec95https://doi.org/10.1155/2022/9947068
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