Key result
Surgical and endovascular correction of atrial septal defect restores decreased heart rate variability to normal levels within 3 to 6 months post-intervention.
Why the study?
Does surgical or endovascular correction of atrial septal defect improve heart rate variability in patients with ASD?
Does surgical or endovascular correction of atrial septal defect improve heart rate variability in patients with ASD?
Surgical and endovascular closure of atrial septal defects normalizes heart rate variability by reducing right heart volume overload and restoring autonomic balance within 3 to 6 months.
V poslednĂch desetiletĂch se znaÄnĂ˝ zĂĄjem soustĹeÄuje na studium vlivu autonomnĂho (vegetativnĂho) nervovĂŠho systĂŠmu na srdce a jeho hodnocenĂ jako prediktoru mortality v dĹŻsledku postiĹženĂ srdce a rozvoje kardiovaskulĂĄrnĂch komplikacĂ. AnalĂ˝za variability srdeÄnĂ frekvence (heart rate variability, HRV) pĹedstavuje jednoduchou, neinvazivnĂ a bezpeÄnou metodu studia regulace kardiovaskulĂĄrnĂho systĂŠmu ÄlovÄka autonomnĂm nervovĂ˝m systĂŠmem. Podle nÄkterĂ˝ch autorĹŻ mĹŻĹže - u pacientĹŻ se strukturĂĄlnĂmi defekty septa - zmenĹĄenĂ HRV v dĹŻsledku objemovĂŠho pĹetĂĹženĂ srdce vyvolat zvýťenĂ tlaku v srdeÄnĂch oddĂlech, pĹĂpadnÄ dysfunkci baroreceptorĹŻ s nĂĄslednĂ˝m vegetativnĂm doprovodem. BÄhem operace mĹŻĹže velmi snadno dojĂt k naruĹĄenĂ homeostĂĄzy neurovegetativnĂho systĂŠmu, z ÄehoĹž vyplĂ˝vĂĄ moĹžnost vlivu perioperaÄnĂho stresu na autonomnĂ nervovĂ˝ systĂŠm. PĹes ÄetnĂŠ studie stĂĄle jeĹĄtÄ existuje holistickĂ˝ pĹĂstup k hodnocenĂ odpovÄdi organismu na chirurgickĂŠ vĂ˝kony u pacientĹŻ podstupujĂcĂch kardiochirurgickĂŠ vĂ˝kony. ObecnÄ platĂ, Ĺže snĂĹženĂĄ HRV po kardiochirurgickĂ˝ch vĂ˝konech se v pooperaÄnĂm obdobĂ bÄhem nÄkolika mÄsĂcĹŻ vracĂ k normĂĄlu. Tento ÄlĂĄnek je pĹehledem literatury s charakteristikami HRV u pacientĹŻ s defektem septa sĂnĂ i jejĂ dynamiky po chirurgickĂŠ a endovaskulĂĄrnĂ korekci defektu pod rentgenovou kontrolou. ÄlĂĄnek rovnÄĹž upozorĹuje na moĹžnou patofyziologii uvedenĂ˝ch abnormalit autonomnĂho systĂŠmu.
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Shvartz et al. (2018) conducted a review in Atrial septal defect. Surgical and endovascular correction vs. Pre-operative baseline or healthy controls was evaluated. Surgical and endovascular correction of atrial septal defect restores decreased heart rate variability to normal levels within 3 to 6 months post-intervention.
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