Key result
Age ≥75 with AMI linked to less invasive treatment, delayed reperfusion, and higher in-hospital mortality.
Why the study?
Despite the widespread elderly population, elderly patients are underrepresented in clinical trials.
Observational
Yes
Answers are grounded in this paper and cite their sources.
Elderly patients (≥75 years) with MI in Russia represent a high-risk group with higher in-hospital mortality and less frequent use of invasive treatments and guideline-directed therapies.
Despite widespread elderly population, these patients are underrepresented in clinical trials. Considering the Russian prospective registry REGION-IM, the authors analyzed anamnestic, demographic and clinical characteristics of patients with acute MI over ≥ 75 years old, treatment features and in-hospital mortality. The results were compared with the data of Russian and foreign ACS registries. Patients with MI ≥75 years old in the Russian Federation are characterized by severe comorbidities, less frequent invasive treatment and prescription of necessary drugs. Elderly patients have longer patient-associated reperfusion delay, symptom-to-diagnosis and symptom-to-hospitalization time, which may be explained by atypical symptoms, mental problems and social factors. In-hospital mortality is much higher in patients ≥75 years old. Elderly patients with MI represent a high-risk group that dictates the need for active and balanced approach at all stages of treatment.
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Gulyan et al. (2025) conducted an observational in Acute myocardial infarction. Age ≥75 years vs. Younger patients was evaluated on In-hospital mortality and treatment features. Patients aged ≥75 years with acute myocardial infarction in Russia experienced less frequent invasive treatment, longer reperfusion delays, and higher in-hospital mortality.
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