High brachial-ankle pulse wave velocity was associated with a significantly increased risk of cardiovascular events or cardiovascular death compared to low velocity (OR 2.74).
Meta-Analysis (n=13,346)
Does brachial-ankle PWV measurement predict future cardiovascular events in patients with cardiovascular disease and/or risk factors?
Brachial-ankle PWV is a useful, simple, and standardized marker for risk stratification and predicting future cardiovascular events in patients with or at risk for cardiovascular disease.
Odds Ratio: 2.74 (95% CI 1.85–4.06)
Since 2001, brachial-ankle pulse wave velocity (brachial-ankle PWV) measurement has been applied for risk stratification of patients with atherosclerotic cardiovascular disease and/or its risk factors in Japan. Measurement of the brachial-ankle PWV is simple and well standardized, and its reproducibility and accuracy are acceptable. Several cross-sectional studies have demonstrated a significant correlation between the brachial-ankle PWV and known risk factors for cardiovascular disease; the correlation is stronger in subjects with cardiovascular disease than in those without cardiovascular disease. We conducted a meta-analysis, which demonstrated that the brachial-ankle PWV is an independent predictor of future cardiovascular events. Furthermore, the treatment of cardiovascular risk factors and lifestyle modifications have been shown to improve the brachial-ankle PWV. Thus, at present, brachial-ankle PWV is close to being considered as a useful marker in the management of atherosclerotic cardiovascular disease and/or its risk factors.
Tomiyama et al. (Tue,) conducted a meta-analysis in Cardiovascular disease and/or risk factors (n=13,346). High brachial-ankle pulse wave velocity (baPWV) vs. Low baPWV was evaluated on Cardiovascular events or cardiovascular death (OR 2.74, 95% CI 1.85-4.06). High brachial-ankle pulse wave velocity was associated with a significantly increased risk of cardiovascular events or cardiovascular death compared to low velocity (OR 2.74).