Key result
The credibility of cardiac electrophysiological models depends on a wide range of distinct factors, including various types of validation results, underlying theory, and evidence from model calibration across multiple scales.
Design
Review
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Multifaceted validation required before clinical or regulatory use; leaves open unified credibility frameworks for cardiac models.
This review clarifies the rationale for the trustworthiness of cardiac electrophysiological models by categorizing the wide-ranging body of credibility evidence, aiding their translation into clinical and regulatory decision-making.
Pathmanathan et al. (2018) conducted a review in Cardiac electrophysiology modeling. Multiscale Models of Cardiac Electrophysiology was evaluated. The credibility of cardiac electrophysiological models depends on a wide range of distinct factors, including various types of validation results, underlying theory, and evidence from model calibration across multiple scales.
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