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July 17, 2022Iranian Journal of Public HealthOpen Access

Estimation of 10-Year Risk of Cardiovascular Diseases Using WHO Risk Prediction Charts: A Population-Based Study in Southern Iran

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Key result

Illiteracy was strongly associated with an increased 10-year risk of cardiovascular disease compared to having an academic degree (aOR 5.79).

Why the study?

Accurate diagnosis and subsequent evidence-based treatment for high-risk individuals is an effective strategy for primary prevention of cardiovascular disease.

Population

8138 participants of the Pars cohort study in southern Iran

Design

Population-based cross-sectional cohort analysis

Authors

FRFatemeh RezaeiJahrom University of Medical SciencesMSMozhgan SeifShiraz University of Medical SciencesMFMohammad Reza FattahiShiraz University of Medical Sciences

Discussion

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Member takes

Overview

Low literacy may flag higher-risk adults for prevention; hypothesis-generating and requires prospective trials before practice change.

Study Design

Type

Cross-Sectional (n=8,138)

Multicenter

No

Structured PICO

P
Population
8,138 adults aged 40-75 years without a history of cardiovascular disease or stroke from Southern Iran, assessed for 10-year cardiovascular risk.
O
Outcome
10-year risk of fatal and non-fatal events of CVD (myocardial infarction and stroke) estimated using the updated 2019 WHO CVD risk prediction charts

Main Result

Odds Ratio: 5.79 (95% CI 3.77–8.88)

Absolute Event Rate: 36.71% vs 9.54%

p-value: p=<0.001

Nearly one-fourth of middle-aged adults in southern Iran have a moderate or higher 10-year risk of cardiovascular disease, driven by modifiable risk factors like abdominal obesity and physical inactivity.

Limitations

  • Cross-sectional nature of the study
  • Results cannot be generalized to people under 40 years
  • Participants were ≥40 years old, so results cannot be generalized to people under 40 years

Cite This Study

Rezaei et al. (2022) conducted a cross-sectional in Cardiovascular Disease risk (n=8,138). Illiteracy vs. Academic degree was evaluated on 10-year CVD risk ≥10% (aOR 5.79, 95% CI 3.77-8.88, p=<0.001). Illiteracy was strongly associated with an increased 10-year risk of cardiovascular disease compared to having an academic degree (aOR 5.79).

synapsesocial.com/papers/6a20c1e66aba112f1d3379fbhttps://doi.org/10.18502/ijph.v51i7.10101
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prevalence of coronary artery disease risk factors in Iran: a population based survey2007 · 259 citations
  2. 22014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults2013 · 8,070 citations
  3. 3PARS risk charts: A 10-year study of risk assessment for cardiovascular diseases in Eastern Mediterranean Region2017 · 42 citations
  4. 4Estimation of total cardiovascular risk using the 2019 WHO CVD prediction charts and comparison of population-level costs based on alternative drug therapy guidelines: a population-based study of adults in Bangladesh2020 · 34 citations
  5. 5Burden of cardiovascular diseases in the Eastern Mediterranean Region, 1990–2015: findings from the Global Burden of Disease 2015 study2017 · 97 citations