Key result
Higher waist circumference and triglycerides are directly linked to pre-hypertension in men and women.
Why the study?
What are the main factors associated with pre-hypertension in Tehranian adults?
Cross-Sectional (n=4,640)
What are the main factors associated with pre-hypertension in Tehranian adults?
Effect estimate: Men: β=0.25 for WC, β=0.11 for TG; Women: β=0.21 for WC, β=0.09 for TG
p-value: p=<0.01
Triglyceride levels and waist circumference are direct modifiable risk factors for pre-hypertension in Iranian adults.
May identify modifiable targets for pre-hypertension; hypothesis-generating and requires prospective validation before clinical adoption.
BACKGROUND: Pre-hypertension is proposed as an independent risk factor for the incidence of cardiovascular diseases. OBJECTIVES: This study aimed to explore the main factors associated with pre-hypertension via testing a hypothesized model in Tehranian adults. METHODS: The study was conducted within the framework of the Tehran Lipid and Glucose Study (TLGS) between 2009 - 2011 on 4640 adults without hypertension, aged ≥ 20 years. RESULTS: = 190.7, P < 0.001). Age, waist circumference (WC), and serum triglyceride concentrations (TG) were directly associated with pre-hypertension in both men (β = 0.16, β = 0.25, and β = 0.11, respectively) and women (β = 0.16, β = 0.21 and β = 0.09, respectively). Physical activity, only in men (β = 0.07), and marital status only, in women (β = -0.06), were also directly associated with pre-hypertension. Both healthy and poor dietary patterns showed indirect associations with pre-hypertension in both genders via WC and TG. Higher age and lower education in both genders, being married only in men, and unemployed status only in women, were positively associated with pre-hypertension via behavioral and cardio-metabolic factors. CONCLUSIONS: Level of TG and WC in both genders are direct modifiable associated factors of pre-hypertension. These findings could be considered in designing future health promotion programs aimed at preventing high blood pressure and its consequences among Tehranian adults.
No takes yet. Share an insight, caveat, or question.
Taherian et al. (2018) conducted a cross-sectional in Pre-hypertension (n=4,640). Cardio-metabolic risk factors (waist circumference and triglycerides) was evaluated on Pre-hypertension (Men: β=0.25 for WC, β=0.11 for TG; Women: β=0.21 for WC, β=0.09 for TG, p=<0.01). Higher waist circumference and serum triglyceride concentrations were directly associated with pre-hypertension in both men (β=0.25 and β=0.11) and women (β=0.21 and β=0.09).
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: