Why the study?
Does right atrial pacing reveal abnormal left ventricular end-diastolic pressure responses in patients with idiopathic mitral valve prolapse compared to normal patients?
Does right atrial pacing reveal abnormal left ventricular end-diastolic pressure responses in patients with idiopathic mitral valve prolapse compared to normal patients?
Patients with idiopathic mitral valve prolapse exhibit abnormal left ventricular diastolic function during atrial pacing, independent of mitral regurgitation.
Abnormal LV diastolic response during pacing in MVP warrants clinical attention; leaves open prognostic and therapeutic implications.
The response of several parameters of left ventricular function to right atrial pacing was compared in 21 patients with idiopathic mitral valve prolapse and 10 normal patients. An inability to appropriately lower left ventricular end-diastolic pressure with increasing rates was demonstrated in the mitral valve prolapse group. This abnormality was not related to mitral regurgitation or factors other than ventricular performance per se.
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Feitosa et al. (1978) studied this question.
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