Key result
A negative interventricular pressure gradient between the left and right ventricles during diastole was found to cause diastolic bulging of the interventricular septum toward the left ventricle.
Why the study?
Does a negative interventricular pressure gradient cause diastolic bulging of the interventricular septum toward the left ventricle in patients with pulmonary hypertension?
Population
n=4 patients and a dog model of acute right ventricular hypertension.
Design
Case_series
Authors
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May explain diastolic septal bulging on echo in pulmonary hypertension; leaves open prospective validation of the mechanism.
Observational (n=4)
Does a negative interventricular pressure gradient cause diastolic bulging of the interventricular septum toward the left ventricle in patients with pulmonary hypertension?
Diastolic bulging of the interventricular septum toward the left ventricle on echocardiography is a reliable manifestation of a negative interventricular pressure gradient during diastole, typically seen in right ventricular hypertension.
Tanaka et al. (1980) conducted an observational in Pulmonary hypertension (n=4). Negative interventricular pressure gradient was evaluated on Diastolic bulging of the interventricular septum toward the left ventricle. A negative interventricular pressure gradient between the left and right ventricles during diastole was found to cause diastolic bulging of the interventricular septum toward the left ventricle.
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